Research has shown that up to two-thirds of the aging HIV population could be affected by prefrailty.
Cognition
- Prefrailty (defined as 1 or 2/5 of the leading symptomsaccording to Fried criteria) affects up to two-thirds of older people, who live with HIV.
Why this matters
- The primary factors driving frailty in older people with HIV should be addressed to counteract an adverse outcome.
Key results
- There were 510 Individuals living with HIV, most of whom were male (median age: 73 years), included in the analysis; 13.1 % (n = 67/510) were ≥ 80 years, 60 % (n = 306/510) exhibited multimorbidities (≥ 3 comorbidities).
- Overall, the prevalence of frailty was (≥ 3/5 Frailty criteria) 13.5 %, the prefrailty prevalence 63.3 %, and 23.2 % were classified as robust (0/5 Frailty criteria).
- Compared to those affected by prefrailty and robust participants, participants with frailty were older, had elevated blood pressure, were more likely to have peripheral arterial disease or chronic respiratory disease, depression symptoms / self-reported mood disorders on and in their history were negative health results in the past year.
- A multivariate analysis showed that the risk of frailty was increased by almost 2 times each by older age and multimorbidities and by 3.17 times by socioeconomic status.
Study design
- French, multicenter, prospective observational study evaluating frailty prevalence, prefrailty prevalence and risk factors associated with frailty in older (≥ span> 70 years) People living with HIV
- Funding: Agence Nationale de Recherche sur le SIDA et les Maladies Infectieuses Emergentes, other sponsors
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Restrictions
- No concerted controls
- Uncertainty about how prefrailty develops in this population over time.
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Source — https://www.univadis.de/viewarticle/sollte-prefrailty-bei-menschen-mit-hiv-fruher-entgegengewirkt-werden
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