Key messages In patients belonging to gender minorities and sexual orientation, breast cancer diagnosis, treatments and outcomes are reduced and different compared to heterosexual/cisgender patients. In a case-control study, published in JAMA oncology, 92 patients belonging to different gender or sexual minorities (sex and gender minority, SGM) were compared with as many heterosexual and cisgender […]
Core messages A lot has happened in the diagnosis and therapy of patients with venous diseases in recent years. In a recent publication, Professor Markus Stücker (Vein Center of the Dermatology and Vascular Surgery Clinics, St. Maria-Hilf-Krankenhaus, Bochum) has shown what in everyday clinical practice at Venous disorders are important. The first episode of a […]
Berlin (pag) – Federal Health Minister Prof. Karl Lauterbach (SPD) describes the new, nationwide campaign to combat the corona virus as a «campfire of the reasonable». The motto is «I protect myself». «My name is Margarete Stokowski and I am here today as a deterrent for Long Covid.» This is how the author describes her […]
The At its meeting in February 2023, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommended the following two medicinal products for approval: pegunigalsidase alfa (Elfabrio, Chiesi Farmaceutici) Recombinant human α-galactosidase-A should be indicated as long-term enzyme replacement therapy in adult patients with a confirmed diagnosis of Fabry […]
During the Clinical evaluation of subjects with a recent history of head trauma is possible to find one or more of the following clinical signs: unilateral or bilateral blepharo-hematoma, blood otorrhea, rhinorrhea and Battle’s sign (retro-auricular ecchymosis). These clinical signs in the diagnosis of basilar skull fracture (BSF) are ambiguous, but widely used to make […]
Rome, Dec. 16. (Adnkronos Health) — A low level of HDL cholesterol, the so-called good cholesterol, is associated with a higher chance of developing hepatocellular carcinoma and seems to be able to predict liver cancer 5 years before diagnosis. This is what emerges from a study by the Aldo Moro University of Bari, supported by […]
These first responders are often on site faster than the emergency services. Insight If randomly present first responders arrive at the site of a cardiac arrest outside the hospital due to a smartphone warning from the emergency services (OHCA), patients are more likely to receive defibrillation by first responders. An increased program for volunteer first responders […]
SIF Societa’ Italiana di Farmacologia Nightmares associated with metformin treatment Edited by Alessandra Russo. Specialist in Medical Toxicology. Messina Clinical case A 40-year-old man with diabetes reported that in the last 3 weeks almost every night he had nightmares. A month earlier he had started taking metformin (500 mg BID), combined with an appropriate diet […]
Core messages An international research team has succeeded in deciphering Ludwig van Beethoven’s genome using five genetically matching locks of the composer’s hair. The evaluation shows that Beethoven had a hereditary predisposition to cirrhosis of the liver and was infected with hepatitis B, which — in conjunction with his alcohol consumption — probably led to […]
Integrated management of major trauma from the scene of the event to the definitive cure Recommendation 37 of the Guideline (updated November 2022) This document represents the final version of the clinical recommendations that have completed the entire process envisaged by the Methodological Manual for the production of guidelines of the Istituto Superiore di Sanità, […]