27 июня, 2021

OFO7788 is the new approach for the cirrhosis treatment

The drug with the codenamed OFO7788 for the cirrhosis treatment is the latest development of Japanese scientists. Multistage clinical trials have yielded results showing that the drug stops inflammation in liver tissue, the process of necrotization of liver cells, and starts regeneration of hepatocytes. This confirmed the assumption that the best cure for cirrhosis is […]

19 июня, 2021

Internists, ‘diabetes alarm in the ward, guidelines to manage it’

Milan, 17 Mar. (Adnkronos Salute) – “More and more people suffering from diabetes or high blood sugar are hospitalized in Italian hospitals, in surgical departments, as well as in those of medicine or specialists. But it is not always possible to consult a diabetologist to set up an adequate diagnostic-therapeutic procedure. Yet properly managing diabetes, […]

17 июня, 2021

Proton pump inhibitors increase the risk of gastric cancer

Insight Proton pump inhibitors (PPIs) are associated with an increased risk of gastric cancer, especially with the non-cardiac type. Why this matters PPIs are commonly prescribed for gastric ulcer, gastroesophageal reflux disease, dyspepsia and Helicobacter pylori eradication, as well as in patients using certain medicines (, NSAIDs, etc.). Study design Meta-analysis of 16 cohort and […]

14 июня, 2021

Global impact of the COVID-19 pandemic on cerebrovascular events

Highlights Background During the first wave of the COVID-19 pandemic, decreases in admission volumes for stroke, intravenous thrombolysis, and mechanical thrombectomy were reported. There is a paucity of data on the long-term effect of the pandemic on systolic volumes over the course of a year and during the second wave of the pandemic. We sought […]

10 июня, 2021

Visceral fat and response to therapy, there is no relationship in rectal cancer

Patients Obese and overweight with locally advanced rectal cancer are as likely to respond to neoadjuvant chemoradiotherapy (nCRT) as normal weight patients. To say it is a study by the University of Padua that found no association between body mass index (BMI) or body fat composition and survival. However, excess weight affects the complications of […]

2 июня, 2021

Erythritol, a bitter reality for a widespread sweetener

Erythritol, A sweetener widely used as an alternative to common sugar, it would not be entirely safe for health. According to the results of a study published in Nature Medicine, erythritol is associated with the risk of adverse cardiovascular events independently of traditional risk factors.Not only that: a high plasma level seems to favor the […]

22 мая, 2021

CHMP meeting: Indication extensions recommended for four drugs

The At its meeting in February 2023, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommended extensions of the indications for four medicinal products:  Cemiplimab (Libtayo, Regeneron Ireland) The antibody already conditionally approved for other cancers will also be indicated in the first-line treatment of NSCLC in combination […]

20 мая, 2021

La medicina e la politica

La pandemia lo ha mostrato in maniera esplicita: la salute non è solo fatta di medicina personalizzata, ma anche, e tanto, di salute pubblica. E per le scelte di salute pubblica il ruolo della politica è fondamentale. Non solo in termini di quantità di denaro investito, ma anche e soprattutto nel modo in cui questi […]

18 мая, 2021

ASH 2022 – Remission and survival benefit with blinatumomab in B-ALL

Findings In patients with newly diagnosed acute B-cell acute lymphoblastic leukemia (B-ALL) without measurable minimal residual disease (MRD-negative) after initial treatment, the use of blinatumomab in addition to consolidation chemotherapy resulted in a significant improvement in overall survival (OS). This consolidation therapy may represent a new standard of care for this patient population. Why this matters Although […]