16 августа, 2021

SICP – Opioid-induced constipation, towards targeted therapy

Key Messages Opioid therapy is essential for the proper management of patients with moderate to severe pain. Opioid-induced constipation (OIC) is a predictable event, affecting most patients on opioid therapy and related to the physiological presence of MOR receptors in the enteric nervous system. The severity of OIC and its impact on quality of life […]

13 августа, 2021

Important Information Note on Xalkori (crizotinib)

AIFA Agenzia Italiana del Farmaco Important Information Note on (crizotinib) Vision disorders, which pose a known risk with crizotinib use, have been reported in clinical trials in 61% of paediatric patients with anaplastic large cell lymphoma (ALCL) positive for recurrent or refractory systemic anaplastic lymphoma (ANAF) kinase (ALCL) or with tumour Inflammatory Myofibroblastic Tumour (IMT) […]

2 августа, 2021

Arrhythmias: only partially sedative data on GLP-1 receptor agonists

A meta-analysis showed no significantly increased risk for higher doses, except for increased ventricular arrhythmias. Knowledge Therapy with glucagon-like peptide 1 receptor agonists (GLP-1RAs) was not significantly associated with newly occurring arrhythmias overall in patients with type 2 diabetes (T2D) or obesity patients. A higher risk of ventricular arrhythmia was observed for higher doses of GLP-1RA. Why […]

21 июля, 2021

EMA recommends approval of Etranacogen dezaparvovec

The At its meeting in December 2022, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a Recommendation for approval for Etranacogen dezaparvovec (Hemgenix, CSLBehring) given: Gene therapy should be used for severe and moderate haemophilia B (congenital factor IX deficiency) in adult patients without a history of […]

18 июля, 2021

Nuoro, a new model of One Health territorial assistance

Nuoro, 25 Jan. (Adnkronos Salute) – In the ASL 3 of Nuoro takes shape the project to create a new model of territorial assistance of proximity to bring the answers to health needs as close as possible to citizens. A further step in this process took place yesterday morning, in the conference room of the […]

6 июля, 2021

‘Take care of yourself’, an all-female project in Prato

Prato, 24 Mar. – (Adnkronos) – The project “Cura, ut valeas – Prenditi cura di te”, proposed by Fondazione Sandro Pitigliani, Associazione Aurora Donna, Asl Toscana Centro, together with the professionals in aesthetics of Confartigianato Imprese Prato and the tutors of Cna Toscana Centro, was presented in the harpsichord room of the Santo Stefano hospital […]

27 июня, 2021

Sexually transmitted infections have increased worldwide

According to Data from World Health Organization (WHO) of 2021, it is estimated that every year about 374 million people contract one of the following diseases: chlamydia, gonorrhea, syphilis and trichomonas infection. In addition, more than 500 million people are carriers of Herpes Simplex viris (HSV) in a population aged 15 to 49 years.As Cristina […]

27 июня, 2021

Acute lower gastrointestinal bleeding: initial assessment criteria

The acute lower gastrointestinal bleeding (SGIA) is one of the most common reasons for hospitalization, both in Europe and the United States (1). The incidence of SGIA is approximately 20-30 cases per 100,000 person-years and accounts for 20% of gastrointestinal bleeding. It is an event that requires hospitalization in almost all cases and has a […]