
SICP – Opioid-induced constipation, towards targeted therapy
Key Messages Opioid therapy is essential for the proper management of patients with moderate to severe pain. Opioid-induced constipation (OIC) is a predictable event, affecting most patients on opioid therapy and related to the physiological presence of MOR receptors in the enteric nervous system. The severity of OIC and its impact on quality of life […]