Research has shown that up to two-thirds of the aging HIV population could be affected by prefrailty. Cognition Prefrailty (defined as 1 or 2/5 of the leading symptomsaccording to Fried criteria) affects up to two-thirds of older people, who live with HIV. Why this matters The primary factors driving frailty in older people with HIV should be […]
Computed Tomography protocols for clinical indication In the document the essential elements relating to the technical settings of the various districts and apparatuses examined have been considered, taking into account the most frequent clinical pathologies. The draft was drawn up in the full awareness of not being able to prepare a document that reported all […]
Italian Government Decreto Legislativo n.200 – Official Gazette n.304 of – In force Reorganization of the discipline of scientific hospitalization and care institutes Chapter I THE PRESIDENT OF THE REPUBLIC Having regard to Articles 76 and 87, fifth paragraph, of the Constitution; Having regard to the Law , No.129, delegating […]
Key messages With a meta-analysis of 5 randomized trials with a total of less than 300 participants, researchers have found that electroconvulsive therapy tends to be more effective at combating major depression, and also achieves higher response rates and more remissions than ketamine. Background Both the narcotic ketamine and electroconvulsive therapy (ECT) are among the […]
Birds and fish do.Also bees, ants and termites. They form swarms and take advantage of the fact that they are stronger, smarter and faster in the group. But can such swarm intelligence also be transferred to quantum networks? A team led by Tanjung Krisnanda from Nanyang Technological University in Singapore asked itself this question and […]
By Dr. Susanne Heinzl In heart failure patients treated with torasemide or with after discharge from hospital, overall mortality and hospitalization rates are similar. The primary endpoint of all-cause mortality did not differ between the two treatment groups in all predefined subgroups. This was the result of the open, pragmatic TRANSFORM-HF study ((ToRsemide compArisoN with […]
Findings In patients with newly diagnosed acute B-cell acute lymphoblastic leukemia (B-ALL) without measurable minimal residual disease (MRD-negative) after initial treatment, the use of blinatumomab in addition to consolidation chemotherapy resulted in a significant improvement in overall survival (OS). This consolidation therapy may represent a new standard of care for this patient population. Why this matters Although […]
A unicentric study with the genetic material of 112 children who died before the end of the first year of life found that the most common detectable cause of death was single-locus gene disease. In 30% of cases, there would have been therapies that would have had a positive effect on the course of the […]
Key messages In the case of cancer-type liver lesions, infectious causes, including parasitic infections, should also be considered in addition to neoplastic causes. This is what Markus Zachäus, a doctor at Helios Park-Klinikum in Leipzig, and his colleagues recommend. The reason is the clinical history of a 50-year-old man, described in a specialized journal of […]
Colonoscopy screening reduces the incidence and mortality of colorectal cancer (CCR) by enabling detection and removal of precancerous lesions. However, the available evidence on the optimal screening interval is limited. In 2019, a systematic review and meta-analysis on the topic showed that the detection of advanced malignancies within 10 years of a negative screening colonoscopy […]