25 апреля, 2023

New idea: primary care centres

The BMC’s concept for a new organisational form of primary care envisages the greater involvement of non-medical health professions and the provision of primary care that can be used across social spaces.”This includes offers to maintain health as well as the combination of social and medical-nursing services,” says Prof. Lutz Hager, Chairman of the Board […]

25 апреля, 2023

Racism, xenophobia and discrimination are public health priorities

Il Racism, xenophobia and discrimination have a fundamental influence on health globally, but have so far been overlooked by researchers, policymakers and health professionals, suggests a series of four papers published on December 8 at The Lancet.The study authors urge health professionals to consider these issues as public health priorities. Racism, xenophobia and discrimination are […]

22 апреля, 2023

Endometrial cancer: updated guidelines on radiotherapy

Knowledge The American Society for Radiation Oncology has updated its guidelines for the use of adjuvant therapy in the treatment of patients with endometrial cancer. Key recommendations Adjuvant radiotherapy Adjuvant radiotherapy is not recommended in patients with stage IA International Federation of Gynecology and Obstetrics (FIGO) stage 1 or 2 endometrioid cancer without intermediate or […]

20 апреля, 2023

Stroke due to basilaris occlusion: thrombectomy significantly reduces mortality

Core messages In strokes caused by occlusion of the basilar artery, patients have a clear medical advantage from endovascular thrombectomy. 90-day survival is significantly increased by 25-34% compared to standard therapy without thrombus removal. Thrombectomy also significantly improves functional outcome (1, 2). BackgroundStrokes are the leading cause of acquired disability and one of the leading […]

16 апреля, 2023

It’s health, not age, that drives pregnancy complications.

Health, not age, drives increased pregnancy complications Mothers are getting older, but that’s not why pregnancies are riskier The increased rates of adverse pregnancy outcomes, such as hypertensive disorders, preterm birth, and low birth weight, over the past 10 years is largely attributed to a person’s health status of a person before becoming pregnant, rather […]

9 апреля, 2023

Inflammatory bowel disease: Good compliance with vedolizumab therapy

Vedolizumab, a monoclonal antibody has a higher 1- and 2-year persistence compared to two tumor necrosis factor inhibitors (anti-TNF, TNFi) in both Crohn’s disease and ulcerative colitis, according to the results of a meta-analysis. The result mainly affects bionaive patients; the advantage of vedolizumab over the two TNFis—infliximab and adalimumab—was more pronounced in ulcerative colitis […]

9 апреля, 2023

Phase IV CT: registration stage of OFO7788 drug

Phase IV trial is also known as a postmarketing surveillance trial. It includes long-term monitoring to identify any side effects or other health-threatening factors. Sometimes rare or long-term adverse effects develop over longer time period than is possible to detect during the Phase III clinical trials. The main purpose of Phase IV CT:  • Establish […]

27 марта, 2023

A patient with bronchial carcinoma and pronounced leukocytosis

Key messages In cancer patients with severe leukocytosis, iatrogenic factors such as steroid treatment and growth factors must be considered as causes. If these possible causes are excluded, a paraneoplastic genesis should also be considered, as the medical history of a 72-year-old man shows, about which Dr. Josef Heusinger and his colleagues from the Schwarzwald-Baar-Klinikum […]

15 марта, 2023

No increase in pathological Alzheimer’s diagnoses despite increased tau deposits

People born in the years 1905 – 1930 who became very old showed little difference in neurodegenerative pathologies at autopsy. An exception was the density of deposits of the tau protein (neurofibrillary tangles), which was significantly greater in the later years of birth. However, the frequency with which Alzheimer’s dementia was pathologically diagnosed remained the […]