Key messages In a world-first application of CAR T cell therapy, base-edited T cells were administered for the first time to a patient with relapsed T-cell leukemia. For gene editing, a base editing approach was used to prevent the DNA damage that occurs with other gene-editing methods. A patient with relapsed T-cell leukemia was successfully […]
Source – https://www.univadis.de/viewarticle/s/erh%25C3%25B6htes-krebsrisiko-durch-hochverarbeitete-2023a1000419
Pisa, 20 Jan. – (Adnkronos Salute) – Starting next February, 200 men and women aged between 35 and 74, randomly selected among the residents of the Municipalities of Pisa and San Giuliano Terme, will receive an invitation to participate in a survey on their state of health. The people who will take part in the […]
Bepirovirsen is an antisense oligonucleotide that targeting all hepatitis B virus (HBV) messenger RNAs to reduce the levels of viral proteins. A phase 2b, randomized, investigator-unblinded trial was conducted involving participants with chronic HBV infection who were receiving or not receiving nucleoside or nucleotide analogue (NA) therapy. Participants were randomly assigned (in a 3:3:3:1 ratio) […]
SIF Societa’ Italiana di Farmacologia Nightmares associated with metformin treatment Edited by Alessandra Russo. Specialist in Medical Toxicology. Messina Clinical case A 40-year-old man with diabetes reported that in the last 3 weeks almost every night he had nightmares. A month earlier he had started taking metformin (500 mg BID), combined with an appropriate diet […]
SIF Societa’ Italiana di Farmacologia Hypersensitivity syndrome associated with sulfasalazine treatment Edited by Alessandra Russo. Specialist in Medical Toxicology. Messina Clinical case A 52-year-old man was hospitalized following the onset of erythema and papules systemically for 10 days and fever for 2 days. The patient was on sulfasalazine as he was suffering from ulcerative colitis. […]
Key messages Extrapulmonary tuberculosis is often a diagnostic challenge. Rarer manifestations of tuberculosis should be considered especially in case of persistent fever and in the presence of patients from high-incidence countries. Rapid diagnosis and timely treatment are decisive elements for the prognosis of patients. This is underlined by pulmonologist Arne Lüers of the Asklepios Klinikum […]
Anyone who has survived an infection with the coronavirus SARS-CoV-2 is usually well protected from a serious illness with hospitalization or death after 40 weeks. This applies to all virus strains, but the probability of new infection with the variant Omikron BA.1 is significantly higher than with the older virus types, according to the result […]
Teramo, 3 Mar. (Adnkronos Health) – Five surgeons from Saudi Arabia and the United Arab Emirates today “in class” in the operating room at the hospital of Sant’Omero. Foreign doctors arrived at the “Val Vibrata” to attend the SphinKeeper surgery carried out for fecal incontinence and the improvement of the surgical technique. This technique allows to effectively […]
The largest known ant species on earth comes from Germany – at least it was found here in 2003 in the Hessian pit Messel as a fossil: The queens of the Titanomyrma gigantea became more than six centimeters long and reached wingspans of about 15 Centimeters. A similarly large relationship was discovered by paleontologists in Wyoming […]