
No increase in pathological Alzheimer’s diagnoses despite increased tau deposits
People born in the years 1905 – 1930 who became very old showed little difference in neurodegenerative pathologies at autopsy. An exception was the density of deposits of the tau protein (neurofibrillary tangles), which was significantly greater in the later years of birth. However, the frequency with which Alzheimer’s dementia was pathologically diagnosed remained the […]