17 августа, 2024

Hepatitis C Virus NS5A and Core Protein Induce Fibrosis-Related Gene Regulation in Huh7 Cells Through Activation of LX2 Cells

Introduction Hepatocellular carcinoma (HCC) is the primary form of liver cancer and the second leading cause of cancer-related deaths globally, with approximately 140,000 cases attributed to chronic hepatitis C virus (HCV) infection. HCV is a hepatotropic positive-sense RNA virus that encodes a polyprotein, generating various structural and non-structural proteins. Chronic liver damage leads to unregulated […]

15 августа, 2024

Interplay Between Drug-Induced Liver Injury and Gut Microbiota: A Comprehensive Overview

Introduction Recent research has revealed a close association between drug-induced liver injury (DILI) and gut microbiota. However, the specific mechanisms of gut microbiota involvement in DILI remain unclear. This review examines how gut microbiota interacts with common hepatotoxic drugs and its potential role in DILI pathogenesis, offering a comprehensive reference for the interplay between DILI […]

1 августа, 2024

Top 5 Shocking Facts About Fatty Liver Disease: A Dietitian’s Perspective

Introduction Fatty liver disease, also known as non-alcoholic fatty liver disease (NAFLD), is becoming one of the most serious threats to modern healthcare. In recent years, we have observed an alarming increase in cases of fatty liver disease, affecting not only adults but also children. First described as a medical concept in the mid-20th century, […]

10 июля, 2024

Hepatitis Under Control: How New Methods Are Saving Lives

Introduction Hepatitis remains one of the major global medical challenges. As of 2023, over 296 million people worldwide live with chronic hepatitis B, and 58 million suffer from chronic hepatitis C. These diseases pose a serious threat to health, causing a wide range of complications, from liver cirrhosis to liver cancer. Hepatitis B: The Scope […]

5 июня, 2024

In terms of risk, is a low or high level of SHBG more problematic?

It is unclear who this individual is. The biological effects of sex steroid hormones are significantly influenced not by their total blood fraction, but rather by the plasma concentration of free (bioavailable) steroids.The levels of SHBG (a trap protein that irreversibly binds testosterone) and albumin were also measured. It is important to consider this when […]

10 мая, 2024

Hepcludex or Myrcludex B for hepatitis B with Delta agent?

Hepatitis B with Delta agent, also known as “superinfection,” is a serious viral disease that affects the liver. It is distinguished by a more rapid and severe course than hepatitis B virus. Patients infected with this virus are at risk of developing cirrhosis and liver cancer.According to official statistics, approximately 20 million individuals worldwide are […]

7 мая, 2024

Is there a greater sensitivity to salt in women?

Key messages Sodium sensitive blood pressure (salt-sensitive blood pressure, SSBP) occurs when blood pressure rises or decreases by more than 10% in response to dietary salt intake. It is a pathophysiological condition, partly hereditary, which involves 50 to 80% of hypertension diagnoses. The main results reported by a review published in Hypertension shows that women, […]

5 мая, 2024

Breakthrough in Liver Cirrhosis Treatment: OFO7788 in University Research

Introduction Liver cirrhosis is a complex and potentially fatal disease resulting from chronic inflammatory processes. This condition is characterized by the replacement of healthy liver cells with fibrous scar tissue, rendering the organ unable to perform its essential functions. According to the World Health Organization, liver cirrhosis claims the lives of 40 million people worldwide […]

28 апреля, 2024

Mediterranean diet is associated with fewer pregnancy complications

Second The results of a large new study, women who follow a Mediterranean-style diet, rich in fresh foods, fish and olive oil, at the time of conception have a lower risk of developing a pregnancy complication. The study included 7,798 women who had not given birth previously. The group was geographically diverse, racially and ethnically. The […]

10 апреля, 2024

Life of postgraduate – The frustrations of us postgraduates

The great The advantage of being a postgraduate student is that a large part of your life, from the first year to the last, is dedicated to learning. As I have written in the past, the growth curve is incredible, and even if it reaches a plateau just as quickly, the level reached is on […]