Hematology

Findings In patients with newly diagnosed acute B-cell acute lymphoblastic leukemia (B-ALL) without measurable minimal residual disease (MRD-negative) after initial treatment, the use of blinatumomab in addition to consolidation chemotherapy resulted in a significant improvement in overall survival (OS). This consolidation therapy may represent a new standard of care for this patient population. Why this matters Although […]

Conclusions Venous thromboembolism (VTE) is common in oncology and is increasing over time. Risk stratification is essential to balance the risks and benefits of primary thromboprophylaxis. The management of cancer-associated thrombosis (CAT) is specific at different times in the course of cancer. The benefit-risk analysis of anticoagulant therapy should be conducted regularly. Prevention Venous thromboembolic […]

Key messages In patients belonging to gender minorities and sexual orientation, breast cancer diagnosis, treatments and outcomes are reduced and different compared to heterosexual/cisgender patients. In a case-control study, published in JAMA oncology, 92 patients belonging to different gender or sexual minorities (sex and gender minority, SGM) were compared with as many heterosexual and cisgender […]

Berlin (pag) – Federal Health Minister Prof. Karl Lauterbach (SPD) describes the new, nationwide campaign to combat the corona virus as a «campfire of the reasonable». The motto is «I protect myself». «My name is Margarete Stokowski and I am here today as a deterrent for Long Covid.» This is how the author describes her […]

Integrated management of major trauma from the scene of the event to the definitive cure Recommendation 37 of the Guideline (updated November 2022) This document represents the final version of the clinical recommendations that have completed the entire process envisaged by the Methodological Manual for the production of guidelines of the Istituto Superiore di Sanità, […]

Key messages If breast skin hematomas occur spontaneously after radiotherapy for breast cancer, close follow-up examinations and, if they persist, further dermatological clarification is also necessary. This is underlined by the interdisciplinary team of authors led by Antonio Ruiu (Bolzano). The recommendation is based on the history of an 80-year-old patient. The patient and her […]

AIFA Agenzia Italiana del Farmaco Web activation and publication of monitoring cards — Registro — Opdivo (RCC) Users of the Drug Registries subject to Monitoring are informed that, following the publication of the AIFA Determine in the OJ no. 256 of , starting from it is possible to use, under the NHS reimbursement scheme, medicinal […]

Source — https://www.univadis.it/viewarticle/da-avalon-nuove-chance-i-pazienti-con-leucemia-mieloide-2023a10002ci

SIF Societa’ Italiana di Farmacologia Excessive consumption of supplements based on Vitamin B6 (pyridoxine) and peripheral neuropathy. Australian Regulatory Authority By Alessandra Russo. Specialist in Medical Toxicology. Messina The Therapeutic Goods Administration (TGA) has published a warning regarding the risk of developing peripheral neuropathy associated with excessive consumption of Vitamin B6 (pyridoxine) supplements. For full […]

The Commission European has granted conditional marketing authorisation for etranacogene dezaparvovec (Hemgenix), the first and only gene therapy for the treatment of severe and moderately severe haemophilia B (congenital factor IX deficiency) in adults without a history of factor IX inhibitors. The approval means that the product will now be available in all countries of […]