27 июня, 2022

Sweden 2023 EU — Conference on Cancer — EU leaves no stone unturned in the fight against cancer

Il On 1 February, the Swedish Presidency of the Council of the European Union (EU) and the European Commission co-organised a cancer conference entitled ‘Equity, excellence and innovation: modern cancer care for all’, during which leading cancer experts from healthcare and academia and high-level political delegates discussed current cancer prevention strategies in the EU, ways […]

7 мая, 2022

ASH 2022 – A tablet the future of paroxysmal nocturnal hemoglobinuria?

Knowledge Oral monotherapy with iptacopan was shown to be superior to intravenous anti-C5 antibodies in patients with paroxysmal nocturnal haemoglobinuria nocturnal haemoglobinuria (PNH) and residual anaemia. Iptacopan may represent a practice-changing outpatient treatment for suboptimal responses to standard treatment (SoC) and may be a preferred treatment option for all patients with hemolytic PNH. Why this […]

12 февраля, 2022

Opdivo immunotherapy is not associated with haematological toxicity in cancer patients

A meta-analysis reports a lower incidence of haematological toxicity than similar drugs. Context The immune checkpoint inhibitor nivolumab is approved in the United States and Europe for at least 10 types of cancer, including melanoma, non-small cell lung cancer, renal cell carcinoma, and gastric cancers. Nivolumab works by inhibiting the immunosuppressive molecule programmed cell death protein […]

28 декабря, 2021

Computed Tomography protocols for clinical indication

Computed Tomography protocols for clinical indication In the document the essential elements relating to the technical settings of the various districts and apparatuses examined have been considered, taking into account the most frequent clinical pathologies. The draft was drawn up in the full awareness of not being able to prepare a document that reported all […]

14 декабря, 2021

ASH 2022 – Remission and survival benefit with blinatumomab in adults with B-ALL

Findings In patients with newly diagnosed acute B-cell acute lymphoblastic leukemia (B-ALL) without measurable minimal residual disease (MRD-negative) after initial treatment, the use of blinatumomab in addition to consolidation chemotherapy resulted in a significant improvement in overall survival (OS). This consolidation therapy may represent a new standard of care for this patient population. Why this matters Although […]

5 декабря, 2021

Negative screening colonoscopy: when to repeat it?

Colonoscopy screening reduces the incidence and mortality of colorectal cancer (CCR) by enabling detection and removal of precancerous lesions. However, the available evidence on the optimal screening interval is limited.  In 2019, a systematic review and meta-analysis on the topic showed that the detection of advanced malignancies within 10 years of a negative screening colonoscopy […]

30 ноября, 2021

Ten weeks waiting for psychotherapy

Leipzig/Berlin (pag) – The German Depression Aid and Suicide Prevention Foundation (DDH) has published the results of this year’s Germany Barometer Depression. Accordingly, 23 percent of respondents currently suffer from a diagnosed depression, eight percent fall ill every year. Prof. Ulrich Hegerl, Chairman of the DDH, points out treatment offers and talks to those affected.  […]

11 октября, 2021

Monitoring of pharmaceutical expenditure

AIFA Agenzia Italiana del Farmaco Pharmaceutical expenditure monitoring AIFA makes available the documents relating to the monthly monitoring of national and regional pharmaceutical expenditure for the period January / December 2021 (consultative) and January / February 2022. Published on: — All rights reserved and for personal use— Download the full document in PDF format from […]

21 июля, 2021

EMA recommends approval of Etranacogen dezaparvovec

The At its meeting in December 2022, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a Recommendation for approval for Etranacogen dezaparvovec (Hemgenix, CSLBehring) given: Gene therapy should be used for severe and moderate haemophilia B (congenital factor IX deficiency) in adult patients without a history of […]