New Treatment Option for Primary Biliary Cholangitis in Scotland Introduction In a significant development for patients with primary biliary cholangitis (PBC), the Scottish Medicines Consortium (SMC) has officially recommended elafibranor as a second-line treatment option. This marks the first new medication for PBC approved by the SMC in nearly ten years, providing hope for individuals […]
Introduction of antigen prostate-specific (PSA) in the screening and diagnosis of Prostate Cancer (CaP) represented, from the 90s of the last century to the early 2000s, a paradigm shift in the management of the disease, resulting in an increase in the incidence and prevalence of cases due to early diagnosis of CaP, including “indolent” forms […]
AIFA Agenzia Italiana del Farmaco AIFA updates the Transparency Lists to In order to allow the Regions and Autonomous Provinces a homogeneous application of the provisions of art. 9, paragraph 5 of Law no. 178 of 8 August 2002, the Italian Medicines Agency publishes, pursuant to AIFA Directorial Determination no. 166 of the Official Gazette […]
Insight Noncancerous cells and their soluble factors play an important role in resistance to immunotherapy. The composition and activity of tumor microenvironment (TME) can be used as targets of therapies. CD19 T cells with chimeric antigen receptor (CAR) therapy has revolutionized the treatment of the most severe and refractory cases of lymphoma, but more than […]
Users of monitored Drug Registries are advised that, as of , the procedures for implementing risk-sharing agreements, i.e. Managed Entry Agreements (MEAs), are no longer active for registries for the following therapeutic indications: is indicated in adult patients with: chronic phase myeloid leukemia with Philadelphia chromosome positive (CML) Ph ), accelerated or blastic resistant or […]
The At its meeting in December 2022 a Recommendation for approval for Tremelimumab (Imjudo, AstraZeneca): The monoclonal antibody should be used in combination with durvalumab as first-line treatment for adults with advanced or unresectable hepatocellular carcinoma. This full text is unfortunately reserved for medical professionals You have reached the maximum number of articles for unregistered visitors […]
Regione Emilia Romagna (Agenzia Sanitaria e Sociale Regionale) Taking care of those who care The narrative in the training course at the time of Covid-19 The dossier, starting from a methodological choice, that of the narrative approach, describes the origins, methods, objectives and techniques of the training course “Taking care of those who care: laboratory […]
Key messages In a world-first application of CAR T cell therapy, base-edited T cells were administered for the first time to a patient with relapsed T-cell leukemia. For gene editing, a base editing approach was used to prevent the DNA damage that occurs with other gene-editing methods. A patient with relapsed T-cell leukemia was successfully […]
Source – https://www.univadis.de/viewarticle/s/erh%25C3%25B6htes-krebsrisiko-durch-hochverarbeitete-2023a1000419
Second The European Commission’s Joint Research Centre (JRC), around 25% of the world’s annual cancer cases occur in Europe and half of all European citizens will develop cancer at some point in their lives. Artificial intelligence (AI) and big data analytics could help improve the situation. Scientists and politicians discussed the role of AI in […]