- Replacing a modest proportion of time spent sitting with various forms of physical activity (even everyday activities such as walks and gardening) reduced the risk of coronary artery disease (CHD).
Why this matters
- Lack of exercise due to predominant sitting is a measurable and modifiable goal for reducing the risk of CHD.
Study design
- Prospective population-based cohort study with 455,298 adults aged 40–69 years without-_ KVE from the general population (UK Biobank)
- Time spent sitting was the total time spent watching TV, using the computer for non-work-related purposes, and driving.
- Key Outcome: CHD Diagnosis
- Funding: NIH, other sponsors
Key results
- At baseline, an average of 34.7 % of the cohort was 4–5 hours of sitting time daily and 27.4 % at an average of ≥ 6 Hours.
- During a median follow-up of 11 years, 4.4-_% of the cohort received a diagnosis of CHD.
- The participants’ risk of CHD increased 2.4-_nbsp regardless of physical activity; Hours spent sitting per day by 9 % (p <0.001).
- Models suggested that replacing 30 minutes of time spent daily sitting through physical activity reduced the risk of CHD: the risk was reduced by 4 % lower (p <0.001) for structured exercise, by 11 % lower (p <0.001) and by 16 % lower (p <0.001 in structured exercise, 001).
- Replacing 1 hours of sitting time resulted in even greater reductions in CHD risk: the risk was lower by 7 % lower (p <0.001) for structured exercise, by 20 % lower for structured exercise, and by 0.001 for strenuous exercise, and by 30 % lower (p <0.001 for strenuous exercises, 001).
- The benefits were greater among participants who did not meet the physical activity levels recommended by the guidelines.
Restrictions
- The implementation of the measures was self-reported, possibly leading to misclassifications and memory distortions.
- Time spent sitting and physical activity were assessed only once at baseline.
- The participants were predominantly white.
This full text is unfortunately reserved for medical professionals
You have reached the maximum number of articles for unregistered visitors
Comments are closed.