5 августа, 2022

Lower muscle mass linked to increased mortality among cancer survivors

Laut A recent study published in the journal Nutrition found lower muscle mass in cancer survivors associated with a higher risk of all-cause mortality and specific cardiovascular mortality.

The authors explained that cancer is one of the leading causes of death worldwide and that cancer survivors have a higher nbsp compared to people without cancer; Stress from low muscle mass.

In this study, they examined the association of all-cause mortality and specific cardiovascular mortality with the decreased muscle mass of 946 cancer survivors and 1,857 comparators without cancer, using the U.S. National Health and Nutrition Examination Survey conducted by the Centers for Disease Control and Prevention.

Lower muscle mass was slightly more common in cancer survivors than in comparable individuals without cancer (22.2% vs.19,7%).

321 cancer survivors and 495 participants in the comparator cohort died during the follow-up of the study (mean follow-up 10.5 years for survivors and 10.9 years for the comparator cohort). Participants with lower muscle mass had a significantly higher risk of all-cause mortality than participants without reduced muscle mass (p<0.01).

In cancer survivors, lower muscle mass was associated with a 73% higher risk of all-cause mortality and a 113% higher risk of specific cardiovascular mortality. This association was not significant in comparators without cancer.

Authors concluded that «cancer survivors with lower muscle mass have a worse prognosis and may have a higher risk of fatal cardiovascular events.»

«Clinicians should consider monitoring body composition as part of cancer treatment to improve prognosis and cardiovascular health,» the authors said.

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Source — https://www.univadis.de/viewarticle/geringere-muskelmasse-hangt-mit-erhohter-sterblichkeit-bei-krebsuberlebenden-zusammen

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