- 5 bacterial pathogens – Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Klebsiella pneumoniae and Pseudomonas aeruginosa – were collectively responsible for over 50 % of global bacterial deaths in 2019.
Why this matters
- Prevention measures and, especially in very young patients, visits to the doctor should be called upon if infections are suspected.
Key results
- 33 investigated bacterial pathogens were in the year 2019 for 56.2 % (7,7 million) of the estimated 13.7 millions of infection-related global deaths.
- 5 Pathogens – S. aureus, E. coli, S. pneumoniae, K. pneumoniae and P. aeruginosa – caused 54.9 % of all deaths among the bacterial pathogens studied.
- Alone S. aureus was marked with> 1 million deaths linked and in 135 countries are the leading cause of bacterial deaths (especially among people aged> 15 years) followed by E. coli (leading cause in 37 countries), S. pneumoniae (24 countries) as well as K. pneumoniae and Acinetobacter baumannii (each 4 countries).
- Lower respiratory tract and bloodstream infections were for 4.00 and 2.91 million deaths, and peritoneal and intra-abdominal infections were responsible for 1.28 millions of deaths.
Study design
- Systematic modelling study to estimate the number of global deaths associated with 33 clinically significant, antibiotic-sensitive and antibiotic-resistant bacterial pathogens across 11 major infectious syndromes in 2019.
- Funding: Bill &— Melinda Gates Foundation, other sponsors
Restrictions
- Sparse and incomplete data for many low/middle-income countries
- Misclassified deaths
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